By Agence France-Presse
The move comes five months after the leading social network said it was banning all ads related to cryptocurrencies like bitcoin as a way to curb scams.
To place ads on Facebook for cryptocurrencies, companies will need to be pre-approved and offer proof they have licenses or are traded on a public exchange, the company said.
"Given these restrictions, not everyone who wants to advertise will be able to do so," Facebook product management director Rob Leathern said in a statement.
"But we'll listen to feedback, look at how well this policy works and continue to study this technology so that, if necessary, we can revise it over time.
Facebook and other online platforms began cracking down on ads for crypto-related businesses amid concerns over fraud in the burgeoning and largely unregulated sector where currencies can see huge swings.
Fraud is common in the world of red-hot digital currencies such as bitcoin.
Earlier this year, the US Securities and Exchange Commission shut down an initial coin offering by a Texas company called AriseBank.
AriseBank was accused of relying on celebrity endorsers such as boxer Evander Holyfield and social media to cheat investors out of $600 million of its goal of $1 billion for a currency it called "AriseCoin."
Initial coin offerings -- used by some startups to raise billions of dollars -- still won't be able to advertise on Facebook.
Twitter, Google and Snapchat have announced similar bans.
The British government early this year called for global regulation of controversial virtual currencies like bitcoin.
Bitcoin and similar forms of virtual cash are independent of governments and banks and use blockchain technology, where encrypted digital coins are created by supercomputers.
The virtual currency is not regulated by any central bank but is instead overseen by a community of users who try to guard against counterfeiting.