The 6.1-magnitude earthquake that struck at 4.03am, followed by repeated aftershocks, had its epicentre in Hongsa district of Xayaboury province.
A damage-prevention system at the plant was automatically triggered and power generation temporarily halted.
The coal-fired power plant has total installed capacity of 1,878 megawatts.
An initial investigation by Hongsa Power Company Limited found no one injured and no significant damage. The main structure was not affected.
The company – a joint venture of RH International (Singapore) Corp, an indirect subsidiary of Ratch; Banpu Power; and Lao Holding State Enterprise – continues to closely monitor the situation, Ratch said.