Speaking at a keynote at the huge Consumer Electronics Show in Las Vegas, Krzanich said he sees wearables and similar technology taking computing power out of the constraints of the traditional screen and keyboard.
"We're going from a two-dimensional world to a three-dimensional world," he told a CES crowd.
"So computing becomes unwired, and everything becomes smart and connected."
Krzanich unveiled the Intel Curie module, a device the size of a button which is essentially a system chip for smart garments, glasses and other wearables.
"Curie is the next generation of computing," he said at the presentation, where he outlined plans for connected eyewear, garments and drones.
The new trend offers a whole new range or intuitive computing without keyboard or screens or mice.
"It can unleash us," Krzanich said.