The doctor, Kent Brantly, was flown to the United States on August 2 after receiving an experimental serum called ZMapp in Liberia.
According to the Christian charity he was working for, Brantly was in dire condition prior to his departure.
Brantly will make a statement at 11 am (1500 GMT) at Atlanta's Emory University Hospital, where he has been held in isolation since his return.
Officials will also give an update on Nancy Writebol, another US aid worker who was evacuated to Atlanta from Liberia after contracting Ebola.
Brantly's blood tests must come back negative for the virus over a two-day period prior to his release, CNN reported.
Ebola is highly fatal, and can be transmitted through bodily fluids such as vomit, blood or infected stool.
The most extensive known outbreak of the disease is currently raging through much of West Africa, where at least 1,350 have died.
DPA