Diesel exhaust classified as carcinogenic to humans

WEDNESDAY, JUNE 13, 2012
Diesel exhaust classified as carcinogenic to humans

The International Agency for Research on Cancer (IARC), which is part of the World Health Organisation (WHO), has classified diesel engine exhaust as carcinogenic to humans, based on sufficient evidence that exposure is associated with an increased risk f

Dr Christopher Portier, chairman of the IARC working Group, stated that “The scientific evidence was compelling and the Working Group’s conclusion was unanimous: diesel engine exhaust causes lung cancer in humans.” Dr Portier continued: “Given the additional health impacts from diesel particulates, exposure to this mixture of chemicals should be reduced worldwide.“
 Actions to reduce exposure are urged to encompass those working close to the exhaust as well as the general public. The conclusion was announced after a week-long discussion with international experts.
  “The main studies that led to this conclusion were in highly exposed workers. However, we have learned from other carcinogens, such as radon, that initial studies showing a risk in heavily exposed occupational groups were followed by positive findings for the general population. Therefore actions to reduce exposures should encompass workers and the general population," said Dr Kurt Straif, Head of the IARC Monographs Programme.
 Dr Christopher Wild, Director, IARC, said that “while IARC’s remit is to establish the evidence-base for regulatory decisions at national and international level, today’s conclusion sends a strong signal that public health action is warranted. This emphasis is needed globally, including among the more vulnerable populations in developing countries where new technology and protective measures may otherwise take many years to be adopted.”
 In 1988, IARC classified diesel exhaust as probably carcinogenic to humans. An Advisory Group which reviews and recommends future priorities for the IARC Monographs Program had recommended diesel exhaust as a high priority for re-evaluation since 1998.
There has been mounting concern about the cancer-causing potential of diesel exhaust, particularly based on findings in epidemiological studies of workers exposed in various settings. This was re-emphasised by the publication in March 2012 of the results of a large US National Cancer Institute/National Institute for Occupational Safety and Health study of occupational exposure to such emissions in underground miners, which showed an increased risk of death from lung cancer in exposed workers.