The Nikkei lost 518.89 points, or 3.83 per cent, to end at 13,014.87 while the broader-based Topix index was down 35.44 points, or 3.15 per cent, at 1,090.03.
Abe said the government will aim to spur the nation's per capita gross national income by more than 1.5 million yen (15,060 dollars) in 10 years under the his economic growth strategy.
On currency markets at 3 pm (0600 GMT), the dollar traded at 99.57-61 yen, down from Tuesday's 5 pm quote of 100.28-30 yen.
The euro was quoted at 130.32-33 yen, down from 131.02-04 yen late Tuesday, and at 1.3083-88 dollars, up from 1.3064-3068 dollars.//DPA