"We are very happy to be here," he said before meeting the foreign ministers from the 10-nation Association of South East Asian Nations (Asean) in Brunei's capital.
He said the talks would include efforts to come up with a binding code of conduct in the disputed areas of the South China Sea.
Kerry also planned to attend an annual regional security forum of ministers from across the Asia-Pacific on Tuesday to deal with regional issues including the Korean nuclear crisis.
He did not comment on whether or not he would meet Russian Foreign Minister Sergey Lavrov, who was also attending the Asean meetings.//DPA