The reports cite unnamed US officials with ABC News in the United States quoting one as saying the airstrike was "flawless" and the British national Mohammed Emwazi was essentially "evaporated."
"We are assessing the results for a final confirmation, but initial indications are that 'Jihadi John' is no longer on this planet," The Wall Street Journal cites a US official as saying.
The Syrian Observatory for Human Rights, which monitors the Syrian conflict, says four foreign Islamic State fighters, including a senior British leader, were killed in the airstrike Thursday in the militant group's stronghold in al-Raqqa British Prime Minister David Cameron is expected to make a statement later on Friday.