Friday's announcement, which warned Rome's fiscal policy was jeopardising banks' ability to fund the Italian economy, followed last week's decision by Moody's to cut Italy's credit rating to a notch above junk status.
"The negative outlook reflects the risk that the government's decision to further increase public borrowing -- besides exacerbating Italy's already weak budgetary position -- will stifle the incipient recovery of the private sector," S&P said.
The decision indicates the debt grade could be cut in the coming months.
The far-right League and anti-establishment Five Star Movement, ruling in coalition, have refused to curb their big-spending programme which forecasts a public deficit of 2.4 percent of GDP in 2019.
The former centre-left government had pledged to keep next year's deficit to 0.8 percent of GDP in a bid to ease Italy's vast public debt, which amounts to a phenomenal 2.3 trillion euros.
Brussels on Tuesday rejected the new plan outright, accusing Rome of "openly and consciously going against commitments made" and requesting a revision.
But the ratings decision was met with a renewed refusal to budge by League head Matteo Salvini and Five Star chief Luigi Di Maio.
"Are ratings agencies unaware of the global financial crisis?" Salvini said on Friday, while Di Maio said such organisations "do not measure the wellbeing of a country's citizens".
"We will continue! Change is underway," added Di Maio.
The Moody's downgrade, cutting Italy's debt grade to Baa3 from Baa2 -- while setting the outlook at "stable" -- came as international financial watchdogs sounded the alarm over Italy's economic choices.
"By proposing a budget heavy on debt-fuelled spending, the country started clashes both with the European Commission and with the market," said Fidelity International analysts Andrea Iannelli and Alberto Chiandetti.
"Neither has confidence in Italy's projection that its economy will grow at a rate of 1.5 percent or that its current debt path is politically and financially sustainable."
S&P said it could change its outlook to stable if the recovery takes hold and the debt burden stabilises.
Since mid-May, when negotiations to form the coalition in Rome began, Milan's stock exchange has lost more than 20 percent. The FTSE MIB closed down another 0.7 percent on Friday.
The closely watched "spread" -- or difference between yields on 10-year Italian government debt compared to those in fiscally conservative Germany -- has more than doubled, widening from 150 points to 309 points.
The Italian banking sector, which holds 372 billion euros worth of the country's sovereign debt according to the central bank, has been the hardest hit, losing 36 percent on the Milan stock exchange.
'A shared solution'
Rome has until November 13 to present a revised budget to Brussels and faces a heavy fine if it fails to do so.
European Central Bank chief Mario Draghi said Thursday he was confident an agreement could be reached.
In the meantime, the commission insists it wants to avoid all-out war with the populists.
"It's very important for the channels of communication to remain open... and I'm not going to be the one to close them," Economic Affairs Commissioner Pierre Moscovici told AFP on Wednesday.
"We need to find a shared solution because Italy is a country at the heart of the eurozone" and "I can't see an Italy without Europe", he said.
But Salvini insisted this week that the Italian economy is healthy and the new budget "will make it even stronger and will create jobs".
"We open the little letters from Brussels because we have been brought up well. We read them, we reply to them but we won't change a comma of the finance law," he said.
In a briefing to reporters on Friday, an EU official speaking on condition of anonymity said Italy could be the next country to call on the European Stability Mechanism -- which since 2008 has bailed troubled economies such as Greece, Portugal and Spain.
"It's hypothetical for now but that's reality," he said.
Published : October 27, 2018
By : Agence France-Presse Milan