
Moriya started quickly on the back nine on Friday with two birdies in her first four holes of the round at the Wilshire Country Club course to reach a total of eight-under 134.
"I just tried to hit fairways and greens. That’s the key for this week. That’s what I try to do," the former LPGA rookie of the year Moriya said.
American Marina Alex is alone in second after shooting a 68 for a seven-under total while two time major winner Ryu So-yeon is in the hunt two shots back of Moriya after a 65.
Seven time major champion Park In-bee is tied for fourth with South Korean compatriot Ji Eun-hee at five-under 137.
Ko Jin-young shot a 67 and is alone in sixth as five of the top six players are from South Korea to the delight of the galleries this week because Los Angeles is home to a huge South Korean expat community.
Moriya, who also has a sister Ariya on the Tour, rocketed to the top of the leaderboard with a burst of three straight birdies on her back nine.
This is just the second time in her career Moriya has held the 36-hole lead. The first was last season at the Evian Championship, where she finished just one stroke away from making a playoff between Anna Nordqvist and Brittany Altomare.
Last week's tournament champ Brooke Henderson of Canada stumbled to an eight-over 79 and missed the cut along with former major champions Anna Nordqvist, Stacy Lewis and Juli Inkster.